FACILITATING TRANSTHORACIC CARDIOVERSION OF ATRIAL FIBRILLATION WITH AMIODARONE PRE TREATMENT
Abhishek Kumar Sharma
Atrial fibrillation ( AF ) is an important medical problem, being the most encountered sustai 212f52c ned arrhythmia in medical practice. The most efficient way to obtain sinus rhythm is electrical cardioversion. Becaus eof the electrophysiological remodeling that takes place in atria in the first 24 hours after the onset of atrial fibrillation, restoration of sinus rhythm by prompt cardioversion might explain the higher success rate in early intervention. Regarding this aspect the use of teh drug to influence electric remodeling is needed. Amiodarone is used as prophylactic drug therapy to increase the success of EC and to maintain sinus rhythm after restoration.
Aim
To analyse the efficiency of EC in amidarone
sensitized AF towards simple EC in a group of 100 patients with persistent AF from cardilogy clinic in
Method
Using amidarone to increase the rate of success of EC was considered individually for each patient regarding the clinical characteristics. The patients treated with amidarone before EC had more predictors of recurrent AF after restoration of sinus rhythm (associated cardiac pathology, left atrial size, low systolic function, long persistent AF)
Results
From 19 patients in amidarone treated group, 17 were succesfully converted to sinus rhythm.
From the 10 patients not treated before EC with amiodarone 7 were restored to sinus rhythm.
Conclusion
Amiodarone increase the chance of sinus rhythm restoration and maintenance by conversion with external electric shock in patients with persistent AF.
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