Anti HTA- asocieri:

Anti HTA- asocieri:

BIP 2. B1B -selective- metoprolol, carvedilol(1/4) 4. Clonidina

1. IEC   . AVC   5. alfa metil dopa
2. Ca bloc 6. beta+alfa bloc
3. alfa 1 bloc

2. Ce NU se da in HTA + Sarcina: 1. IEC -tub crest = Irenala fat,

2. BRTA1

3. Diuretice- ↓ vol plasm, ↓circul placentara, ↓ nutritia fat

3. Diuretice din HTA: 1. Tiazidice: ICC, HTA -1 varstnic, 2. sistolica izolata varstnic, 3. ..

2. Ansa: ICC, IRenala

3. Aldostero: ICC, Post IMA

4. Indicatii : Aritmice + HTA:

1. BB selective

2. Ca bloc: Verapamil, Diltiazem(dupa ↓ K posttrat diur-favor ectopii V Proaritmigene)

5.Asocieri de:

AA

Amiodarona: Fibroza pulm, neuropat perif, depozite cornee, disf hep, tiroid : Bo pulm, hep

BB: bronhospasm, hiperglicelie : astm, D-Insdep

Ca bloc: ICC, BAV : disf V, tulb cond

Disopiramida: ICC, Tor Vf, Ret. urinara, glaucom, ↑QT, tulb ritm, : QT>, prostatism,IR,glaucom

Flecainida: ↑ mortalitatea Post IM, bradi aritmii : tulb de cond

Procainamida: Sdr. Lupoid , agranulocitoza : artrita cr. Discrazie sg

Lidocaina+ Mexiletina : tremor : Parkinson

Propafenona: ICC, Brspasm, proaritmic : astm, tulb cond, disf VS

Chinidina: Tor vf, ↑ QT, diaree, hipoK : bo. dig cr, QT>, hipoK

Sotalol: Tor vf, Brspasm, DZins dep   : astm, DZinsdep, QT>, hipoK

Brdilat β2Adr: toleranta, agitatie, tremor, nervoza, cefalee, transpir, slabiciuni, roseata pielii, greata, voma, aritmii, HTA, hipoK

Stabilizatori mastocitari: cefalee, gat uscat, brspasm tranzitoriu, tuse, roseata tegum

Imm super : deriv Tioguanina -suprima maduva hematopoetica, Mitutirixative?- supresie medulara, alopecie, nefrotoxic, afect. Epit intest, Inflix- IResp super ↓ Ig A secretoare?

IPP: Omeprazol- Hipergastrinemie secundara, Hiperplazia mucoasei gastrice

Teofilina: C-V: TS, TSV, ESV, FiA, FlA, TahicA, Tahic multifocala, aritmie cu instabil hemodinamica

7. AA neclasificate: 1. Atropina - bradicardie sinusala

2. Adrenalina - stop card

3. Izoprenalina - bloc card

4. Digoxin - FiA

5. Adenozin - TSV

6. CaCl2 - TV prin hiper K

7. M gCl2 - FiA, intoxic cu digitala, Tor vf

8. Ef corticosteroizi: Confirmat - inhib locala: ↓ nev de corticoster sistem, ↓ simpt sau exacerb AB, ↓ nev de brdilat Adr de urgenta, ↓ crize nocturne/echivalent AB nocturn - tuse, imbunatateste indicii calitate vietii, ameteli functie pulm

Posibil: ↓ cz deces, ↓ vit declin fct pulm, ↑ per de remisie sustinuta a crizelor

9. Ef Brdilat: Brdilatatie, stabilizare mastocitara, inhib elib LT, ↓ permeabilμ vasc, ↓ exudat + edem cai aeriene,

↑ clearence mucociliar, ↑ secret mucus

↑ Sv BB in IC : ↓ risc de aritmii -ef anti aritmic prin ↑ activ sinaptice in ICC

clase de madicam in IC: IEC, BB (digoxin, nitriti, diuretice)

12. Cdtii pato HTA + BB : AP, postIMA, ICC, sarcina, tahiaritmii, cele cu acti intrinseca -sunt tahicardizante - CI

13. NU se dau HTA + BB : OBLIGATORII: astm, BPOC, BAV2/3, POSIBILE: b vasc perif, intoler la gluc, pers fizice active - atleti

14. Medicam ce act pe alfa 2 centrali: Clonidina, alfa-metil dopa, Monoxidina, Rilmetidina, Guanfacina

15. Cdtii pat. ce determ Aritmii: TS, durere, hipovol, IC, tireotoxicoza, anxietate

16. In ce aritmii se da Digoxina: FiA : 62,5 -250 μg/zi p.o. corelata cu varsta

17. To vf : MgCl2: 2g in 1-2min, repetat la 5-10min, alternativ Isoproterenol sau Paging(↑QT)

18. Geneza To vf: blocK, antihist, fenotiazidice, antidepresive triciclice, Ketoconazol, dieta proteica, lichida

19. AA ↑ QT: Chinidina, Disopiramida, Amiodarona, Sotalol, Bepidil, Producol, Prenilamida, deriv triciclici, Feniltiazina, Eritromicina, Antihistaminice: Terfenadina, Astemizol, ↑QT pe fond de hipoK,Mg

20. AA ↑ PR(perioada refractara): ..?? IA, IC, III, Sotalol

21. AA PROaritmogene: IA, IC, III, Sotalol

22. Cum actioneaza Cls I pe PR:

23. Cum act Cls I pe PA: IA↑, IB↓

24. Cum act Cls III: ↑ durata Fz 3, ↑ PA, ↑ PR

25. Cum act Cls IV pe Fz 0 : ↓ depolarizarea spontana, ↓ frecventa conducere AV, ↓ PA

26. In ce afect se da Bloc alfa Adr: Hiperplazie de prostata, Hiperlipidemie

27. Cls Laxative:

Volum - metilceluloza, Plicarbophil

Emoliere - Docusat Cu/Na

Lubrefianti - Ol. Parafina/ Magnezia Usta

Iritante - Senna, Fenolftaleina, Ol. Castor, Ol. Ricin

Osmolice - MgSO4, citrat, polietilengliol electroliti = Fortans, Lactuloza - ↓ NH3, encefalie portala

28. Indicatii MgSO4 = laxative osmotice in constipatie, atrag apa = ↓ densit bol fecal

29. UG +HP: Clase:

Anticecretor -IPP: Omepraz40, Lansopraz15-30, Pantopraz40

BRH2 : Cimetidina 800zi, Ranitidina 300, Famotidina 40

Protectoare Bismut 525x3/zi

Antibio... : Metronidazol 400x3/zi Timidazol, Claritromicina 500x2/zi, Amoxicilina 500x3/zi

30. Ef adv Cimetridina: cefalee +/- somn, fatigabilitate, greata, voma, diaree, constipatie, tr-penie, ginecomastie, alopecie, impotenta, atralgie, disc-abd

31. Da Tahicardie reflexa: Clonidina, vasodilat directe, IEC

32. IEC indicatii:   CI:

1. IC toate stadiile :sarcina

2. HTA- cu risc ↑ DZ   : stenoza bilat a art renele

3. IMA, post IM cu disf VS   :HiperK

4. Nefropatie diabetica

5. Protectie CV, postIM remodelare

33. Bo. inf int :Clase:

5Aminosalicilati - Sulfasalozina, Mesalazina - Sulfapiridina 4g/zi in 4 prize initial 500mgx2/zi., similar Olsalazina

GCz Prednison 40mg/zi

Imm Supres : daca nu raspunde la GCz

deriv deTioguamina = 6Mercaptopurina 1,5mg/kg/zi

Azatiopurina 2-2,5mg/kg/zi tipm 3-6 luni

Metotrexat 15-25mg/sapt i.m. ef bun in Bo. Crohn

Ciclosporina 4mg/kg/zi infuzie c% sange tot 300-400mg/ml - ef ↑ in RCUH ce nu rasp la GCz

Infliximab - Ig ce leaga TNFalfa pe care-l neutralizeaza

34. Scopul terapeutic in Astm:

35. Asocieri de diuretice:

36. ce medicam este cunoscut ca fiind hiperglicemiant?

37. Ef nitratilor in IC:

38. Ci in sarcina:

39. Antimimetice- 5med +eficicienta ptr fiecare:

40. consecinte Cls II- Fz 4:

41.Asocieri rationale in HTA:

42. Ce medicam ↑ sensibilit la digoxina?

43. PR in Fz1.:

44. Ce medicam ↑ rezist perif cr.?

45. Ef. Stabilizatorilor mastocitari: